Ex Parte CLARK et al - Page 6



             Appeal No. 2001-2271                                                              Page 6                
             Application No. 08/971,839                                                                              
             stand or fall with claim 1.  Accordingly, the rejection of claims 1, 2, 7, 10 and 11 is                 
             affirmed.                                                                                               
             The Rejection of Claims 1, 2, 7, 10 and 11                                                              
                    Claim 3 specifies that the biological agent is calcein or oxytetracycline                        
             hydrochloride, neither of which is disclosed by Zohar or Heat Systems Ultrasonics.                      
             Thus, the examiner relies on Monaghan and Mohler as evidence that both were well                        
             known in the art as chemical markers “especially when mass-marketing larval fish for                    
             long-term hatchery product evaluation” (Answer, page 8).  Appellants argue that the                     
             Monaghan and Mohler references “are not relevant to the claimed distinction involved                    
             herein,” i.e., maintaining a constant temperature during ultrasonification, “even though                
             they are relevant to other limitations of the second group of claims” (Brief, page 5).                  
                    Inasmuch as we have found no error in the examiner’s determination that Zohar                    
             and Heat Systems Ultrasonics are sufficient to establish that “it would have been prima                 
             facie obvious . . . to maintain the temperature constant at a temperature . . . during [ ]              
             ultrasonic . . . infus[ion of] compounds into aquatic organisms,” and appellants agree                  
             that Monaghan and Mohler “are relevant to other limitations of the second group of                      
             claims,” we affirm the examiner’s rejection of claims 3-5, 8 and 13 as well.                            
















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