Appeal No. 2003-0480 Page 7 Application No. 08/090245 Conover detects analytes via detection of a product of an enzyme-catalyzed reaction.” In conclusion, appellants argue (Brief, page 13), “the combination of Schochetman and Schenck would yield a device for measuring the rate of catalysis and not analyte concentration.” We note, however, that claim 83 does not require the measurement of analyte concentration. Claim 83 requires only that the catalytically active antibody or fragment catalyze a chemical reaction (e.g., a physical or chemical change in an environment) that is detected by the sensing means. In our opinion, measuring the rate of catalysis, as appellants admit is taught by Schochetman and Schenck, is just such a physical or chemical change in an environment as is required by claim 83. Accordingly, we affirm the rejection of claim 83 under 35 U.S.C. § 103 as being unpatentable over Schochetman in view of Schenck and Conover, further in view of appellants statements as to the state of the art at pages 3-6 of the specification. As set forth above, claim 84 falls together with claim 83. Claim 85: According to the examiner (id.), claim 85 “requires that the catalytic antibody be ‘contained in or on a cell, a component of a cell, or a tissue.’ A component of a cell is literally any … molecular fragment or molecule found therein. Thus immobilization on a cellulose acetate membrane, both cellulose and acetate are components of cells, would suffice to meet the required limitation.”Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007