Interference No. 103,675
multiplicity; mass spectrum analysis; and, an empirical formula.
The compound obtained in Example 2 is defined as "white
amorphous solid" and being a 1:1 mixture of "- and ß-isomers of the
named compound. Also included are characteristic NMR spectra as
identified by chemical shifts compared to deuterated chloroform as an
internal standard.
The compound prepared in Example 3 is described as a "white
solid". There are also included the NMR characteristics defined by the
chemical shifts for the compound compared to deuterated chloroform as
an internal standard. According to the description of how the compound
of Example 3 was synthesized, the "- and ß-isomers were separated by
high pressure liquid chromatography (HPLC).
Intermediate compound IIIa prepared according to Example 4
is described as an "amorphous solid." According to the description of
the synthesis in the example, the NMR spectra for compound IIIa was
"essentially identical to that reported in Example 2." Upon
deprotection of the 2'-position in compound IIIa 7-"-fluorotaxol was
obtained. Although no NMR data are set forth in the example, the NMR
spectra was said to be "consistent for the structure." The calculated
molecular weight (856.3344) for the sample was substantially the same
as the molecular weight as determined by mass spectrum (856.3367).
In Example 5, the named product obtained is described as a
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