Interference No. 103,675
the count. Additionally, CX 18 has an illegible signature of a person
alleged to have "witnessed" Dr. Chen's notebook. Similarly, CX 19 has
an illegible signature of a person alleged to have "witnessed" Dr.
Chen's notebook more than one month after the date on which Dr. Chen
completed the experiment set forth on page 015 of Notebook Number
30347. Although Dr. Chen has testified that he performed an NMR
analyses on the reaction product and determined that the "major
product" had been obtained in a 50% yield, there is no indication
anywhere on either CX 18 or CX 19 which shows any NMR analyses had
been performed by Dr. Chen or explains how Dr. Chen separated the
reaction products and determined the yield. No witness who allegedly
signed the notebook pages has testified.
In CX 20, the synthesis of 7-fluoro derivatives of protected
taxol is described. These compounds are not compounds within any of
the counts. According to the date at the top of the page and Dr.
Chen's testimony concerning his ordinary practice of making entries in
his notebooks, the experiment was started on October 8, 1990, the date
at the top of notebook page 025, and was completed by Dr. Chen on
November 1, 1990, the date on which Dr. Chen signed the bottom of
notebook page 025. Again an illegible signature of a person alleged to
have witnessed Dr. Chen's notebook is found at the bottom of the page.
The date of the "witnessing" is September 6, 1995, almost five years
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