Interference No. 103,675
Dr. Golik, a Bristol-Myers Squibb employee received a 30.5 milligram
sample of a compound identified to him by Dr. Chen as 7-deoxy-8-
desmethyl-7,8-cyclopropylbaccatin III (CR 146; CX 211). Dr. Golik
testified that Dr. Chen explained to him that Dr. Chen had prepared
the sample by "treating 7-deoxy-desmethyl-7,8-cyclopropyltaxol with
tetrabutylammonium borohydride" (CR 147). Dr. Golik wrote the reaction
Dr. Chen explained to him for preparing the compound in his laboratory
notebook number 30614, page number 094. Thus, Dr. Golik's knowledge
was not independent but obtained directly from Dr. Chen, an inventor.
In late August 1992, Dr. Golik transferred a recrystallized
sample of the compound given to him by Dr. Chen to Dr. Gao with a
request for x-ray diffraction analysis (CR 148; CX 212). The request
form included the structure for the compound as proposed by Dr. Chen.
Dr. Gao performed an x-ray diffraction experiment on the sample in
early September 1992. According to Dr. Gao's testimony, after her
mixed results experimenting to find a suitable solvent for
crystallizing the compound, she "solved" the structure on September 8,
1992, of the compound submitted by Dr. Golik from data generated in
her experiment on September 4, 1992 (CR 163). According to her
testimony, Dr. Gao "confirmed that the proposed structure was
correct." Id. The proposed structure was the structure which Dr. Chen
had previously furnished to Dr. Golik. Dr. Gao wrote up her findings
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