CHEN et al. v BOUCHARD et al. - Page 116



          Interference No. 103,675                                                      

    "consistent" with Dr. Chen's proposed structure and Dr. Kingston's                  
    after the fact conclusion that the spectra obtained were "consistent"               
    with Dr. Chen's proposed structure are not independent analysis or                  
    even knowledge independent of Dr. Chen because they each relied on Dr.              
    Chen's proposed structure for purposes of their analysis. Frilette v.               
    Kimberlin, supra. Further, Huang testified that she relied on more                  
    than simply the spectra (CR 664, line 3 through CR 667, line 3; and CR              
    674, lines 3-19). In other words, the spectra alone would have been                 
    insufficient to "prove" the structure of the sample compound. Dr.                   
    Kingston's reference to CX 57 as being "consistent" with the proposed               
    structure also relies on the representations of Dr. Chen and therefore              
    cannot be said to be knowledge independent of the inventors. It also                
    cannot be determined from Kingston's conclusion what formed the                     
    underlying basis for that conclusion. As we have stated previously,                 
    NMR spectra in general and these particular NMR spectra specifically                
    are subject to more than one reasonable interpretation. Further, the                
    date the "re-plot" was generated, May 13, 1993, is subsequent to                    
    Bouchard et al.'s effective filing date and, therefore, cannot                      
    establish prior invention by Chen et al.                                            
                                   BMS-183583                                           
              According to Dr. Chen's uncorroborated testimony, in                      
    December 1991, he prepared a sample from a 7-epi-taxol and DAST (CX                 
                                       116                                              


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