Ex Parte HILLMAN - Page 3




              Interference No. 104,436 Paper 98                                                                                  
              Shyamala v.. Hillman Page 3                                                                                        
      [11] When the interference was declared, ShyamaIa had also been accorded the benefit of two                                
              provisional applications                                                                                           
                             60/021,641, filed 12 July 1996, and                                                                 
                             60/021,224, filed 3 July 1996                                                                       
      [12] ffillman successfully at tacked the benefit accorded to Shyamala for its provisional applications.                    
      (13] If Shyamala were still entitled to that benefit, it would be senior party.                                            
              Shyamala's ELJority case                                                                                           
      [14] Dr. Venkatakrishna Shyamala is the named inventor of the subject matter of the Shyamala                               
              claims.                                                                                                            
      [15] According to Dr. ShyarnaIa, she began working on proteins that interact with MKK3 in 1994                             
               1025' at 31.                                                                                                      
      [16] According to Dr. Shyamala, she was interested in MKK3 because it was known to regulate the                            
              activity of p38 kinase, which itself was implicated in biological pathways of clinical interest                    
              [1025 at 3].                                                                                                       
      [17) According to Dr. Shyamala, little was known about proteins interacting with MKK3 other than                           
              p38 kinase [1025 at 3].                                                                                            
      [18) Hamiduddin "Hamid" Khoja was Dr. Shyamala's assistant at the relevant time [1025 at 4-5].                             
      [19] Mr. Khoja declared that he no longer works for Chiron and has no interest in the outcome of the                       
              interference [1010 at 2).                                                                                          




                     1 Declaration of Venkatakrishna Shyarnala, Ph.D.                                                            






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