Ex Parte LUDDECKE et al - Page 6




              Appeal No. 2003-1721                                                                 Page 6               
              Application No. 09/226,143                                                                                


              the Statements in the Specification.3  Moreover, the Examiner does not provide a convincing               
              alternative interpretation.                                                                               
                     The Examiner finds that Kitaoka extracts carotenoids from bacterial cells with                     
              supercritical fluid and, optionally, an entrainer (Answer, p. 4).  While the list of entrainers           
              preferably used by Kitaoka overlaps the list of solvents discussed as useful to form aggregates in        
              the Statement in the Specification, there is no disclosure in Kitaoka, pointed to by the Examiner,        
              that describes adding water to a solvent-carotenoid solution.  Water and the other solvents are           
              listed separately by Kitaoka and no combination of the two is mentioned.  There is no reasonable          
              basis presented by the Examiner indicating that aggregates necessarily form when one of                   
              ordinary skill in the art follows the teachings of the reference.                                         
                     The rejection over Takagaki fails for similar a similar reason: The Examiner has failed to         
              point to a portion of the Takagaki reference that discloses diluting a water miscible solvent-            
              carotenoid solution with water.  First, we note that, contrary to the finding of the Examiner             
              (Answer, p. 5), Takagaki does not teach a carotenoid-acetone solution obtained by extraction              
              with an aqueous medium.  Takagaki only discusses the use of acetone solvent in the production             
              of an organic licorice solvent extract.  Carotenoid is added only after the solvent, is removed           



                     3Appellants’ position is further supported by the underlying documents referred to in the portion of the
              specification relied upon by the Examiner.  All of these references describe diluting a solvent-carotenoid solution
              with water.  See especially A. V. Ruban, P. Horton, A. J. Young, J. Photochem. Photobiol. B: Biol., 21 229-234
              (1993) at p. 230, col. 1, last four lines and p. 231, col. 1, ll. 12-16; V.R. Salares, N. M. Young, P. R. Carey, H. J.
              Bernstein, Journal of Raman Spectroscopy, 6(6), 282-288 (1977) at p. 282, col. 2, “Preparation of solutions”; P.
              Song, T.A. Moore, Photochemistry and Photobiology, 19, 435-441 (1974) at p. 436, col. 2, “Results”.       







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