Ex Parte Douin et al - Page 9


              Appeal No. 2004-0378                                                                                            
              Application No. 09/765,675                                                                                      

              the beneficial properties of both compositions (specifically, storage stability, freeze-thaw                    
              stability, and moisture retention after water washing).  That is, Restle teaches that a                         
              composition having superior storage stability results when a nonionic amphiphilic lipid                         
              and a cationic amphiphilic lipid are included in an oil-in-water nanoemulsion, while                            
              Ziegler teaches that superior freeze-thaw stability results from combining a cationic                           
              polymer with a quaternary ammonium functionalized ester (as the primary surfactant) in                          
              emulsions, including oil-in-water emulsions, that can also contain nonionic surfactant(s).                      
                      Thus, those skilled in the art would have expected that combining all three                             
              ingredients in a single composition would result in a composition having all these                              
              properties.  The references would have supported a reasonable expectation of                                    
              achieving this result, since the components of the emulsions disclosed by Restle and                            
              Ziegler are very similar.  Although Restle’s composition is in the form of a nanoemulsion                       
              (with very small oil globules), Restle does not disclose any properties of nanoemulsions                        
              that would have been expected to interfere with an expectation of achieving a                                   
              composition with freeze-thaw stability or moisture retention properties.3                                       
                      Appellants argue that those of skill in the art would not have been motivated to                        
              combine Ziegler’s cationic polymers (with or without a quaternary ammonium phosphate                            
              ester) with Restle’s nanoemulsion composition.  Appellants argue that the examiner’s                            
              “statements amount to a conclusion that the addition of cationic surfactants and skin-                          
              conditioning cationic polymers to nanoemulsions is prima facie obvious, even without                            
              any specific motivation to select and combine the particular components merely                                  

                                                                                                                              
              3 For example, Restle discloses that prior art oil-in-water nanoemulsions, like other oil-in-water emulsions,   
              had poor storage stability.  See page 3, first paragraph, and page 2, last paragraph.                           





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