Ex Parte Douin et al - Page 11


              Appeal No. 2004-0378                                                                                            
              Application No. 09/765,675                                                                                      

                      We do not agree that the prior art disclosures support only an obvious-to-try                           
              rationale.  “An ‘obvious-to-try’ situation exists when a general disclosure may pique the                       
              scientist’s curiosity, such that further investigation might be done as a result of the                         
              disclosure, but the disclosure itself does not contain a sufficient teaching of how to                          
              obtain the desired result, or that the claimed result would be obtained if certain                              
              directions were pursued.”  In re Eli Lilly & Co., 902 F.2d 943, 945, 14 USPQ2d 1741,                            
              1743 (Fed. Cir. 1990).                                                                                          
                      Here, Appellants have not shown that nanoemulsions were known, to those                                 
              skilled in the art, to differ from other emulsions in a way that would have cast doubt on                       
              the expectation of successfully combining Restle’s and Ziegler’s disclosures.                                   
              Appellants point to the specification’s discussion of nanoemulsions and microemulsions,                         
              but make no effort to explain how the differences between these emulsions would have                            
              led those skilled in the art to doubt the applicability of Ziegler’s disclosure to Restle’s                     
              nanoemulsions.                                                                                                  
                      Appellants also point to the specification’s discussion of problems that can be                         
              encountered when adding thickeners such as Carbopol to nanoemulsions, and the                                   
              different characteristics that result on addition of Quatrisoft LM 200 instead of Carbopol                      
              Ultrez.  Again, however, Appellants have not explained why the known problems with                              
              using Carbopol as a thickener would have led those skilled in the art to doubt the                              
              effectiveness of adding Ziegler’s Quatrisoft LM-200 to Restle’s composition.  This is                           
              especially true since Ziegler does not suggest adding a cationic polymer as a thickener,                        
              but as a component that contributes to freeze-thaw stability and moisture retention.                            







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