Ex Parte Douin et al - Page 15


              Appeal No. 2004-0378                                                                                            
              Application No. 09/765,675                                                                                      

              disclosed in the Restle reference in fact include polymers such as polysiloxane.”                               
              Examiner’s Answer, page 4.  This argument is not a sufficient rebuttal:  even assuming                          
              that the references would have suggested including “polymers such as polysiloxane” in                           
              a nanoemulsion composition, the examiner has made no effort to show that such                                   
              polymers claim 78’s limitation of “comprising at least one hydrophobic block and at least                       
              one hydrophilic block.”  Since the examiner has not shown that the references would                             
              have suggested a composition within the scope of the claims, the rejection of claims 78-                        
              82 is reversed.                                                                                                 
              3.  Claims 23-29 and 63                                                                                         
                      The examiner rejected claims 23-29 and 63 as obvious in view of Restle, Ziegler,                        
              and Simonnet.  We agree that the composition of claim 23 would have been obvious to                             
              those skilled in the art, although not for the reason advanced by the examiner.  Rather,                        
              we conclude that claim 23 would have been obvious in view of Restle and Ziegler, for                            
              the same reason discussed above with respect to claim 1.                                                        
                      Claim 23 is directed to the composition of claim 1, further comprising an                               
              additional amphiphilic lipid, which is either a cationic lipid or one of several listed anionic                 
              lipids.  That is, claim 23 is directed to the nanoemulsion composition of claim 1,                              
              comprising an oil, an amphiphilic lipid (anionic, cationic, or nonionic), and an appropriate                    
              cationic polymer, and additionally comprising a cationic amphiphilic lipid.  Thus, claim                        
              23 reads on the composition made obvious by Restle and Ziegler, because that                                    
              composition comprises an oil, a nonionic amphiphilic lipid, an appropriate cationic                             
              polymer, and a cationic amphiphilic lipid (specifically, a quaternary ammonium                                  
              functionalized phosphate ester).  Since the prior art would have made obvious at least                          





Page:  Previous  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  Next 

Last modified: November 3, 2007