Appeal No. 2004-0615
Application No. 08/761,063
Takase discloses a centripetally-motivated fluid analyzer
comprising a disk (101) having a first flat, planar surface and a
second flat, planar surface opposite thereto (figure 1), wherein
the first surface comprises a multiplicity of flow paths (102)
which can be narrow, shallow grooves (col. 5, lines 38-42 and
52-56). A sample input nozzle (7) is in fluidic contact with the
flow paths (col. 7, lines 25-28). The second surface is encoded
with an optically-readable instruction set for controlling disk
rotational speed (col. 12, lines 4-13 and 29-30) and for
performing an assay (col. 13, lines 38-49). A disk rotating
device (6) is connected to the disk and comprises a
servomotor (4) and a drive control circuit (5), the drive control
circuit being directed by instructions on the disk’s second
surface (col. 7, lines 12-18; col. 12, lines 4-30); figure 1). A
volume of fluid within the flow channels of the platform can be
moved through the flow channels by centripetal force arising from
rotational motion of the disk (col. 5, lines 43-49; col. 9,
lines 28-32).
Takase does not disclose that the flow paths are enclosed
within the first surface. Cottingham’s apparatus is a
centripetally-motivated fluid analyzer having channels which can
be microchannels, the channels and reagent chambers being covered
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