Ex Parte MIAN et al - Page 7




          Appeal No. 2004-0615                                                        
          Application No. 08/761,063                                                  

          the fluid in the test unit and would have fairly suggested, to              
          one of ordinary skill in the art, using Cottingham’s top film 72            
          in Takase’s test unit to perform that function.                             
               The appellants argue that Takase discloses grooves or                  
          troughs and does not disclose microchannels (brief, page 12).  As           
          indicated by the dictionary definitions of record, a groove is a            
          channel.  The appellants’ “[m]icrochannel sizes can range from              
          0.1 m [sic, 0.1 mm] to a value close to the 1mm thickness of the            
          disk”, and preferably “the cross-sectional dimension of the                 
          the [sic] microchannels across the thickness dimention [sic] of             
          the platform is less than 500:m [0.5 mm]” (specification,                   
          page 12, lines 6-7 and 8-11).  Cottingham’s microchannels, which            
          are of the type disclosed in U.S. patent application                        
          no. 08/213,304, issued as patent no. 5,783,148 (Cottingham,                 
          col. 19, lines 3-6), are about 0.006 inches [0.152 mm] high                 
          (‘148 patent, col. 4, lines 15-16).  Takase’s exemplified flow              
          paths are 1-10 mm wide, 50-100 mm long and 0.1-2 mm deep, and               
          Takase teaches that the width and length are not limited (col. 5,           
          lines 52-56).  Because the depth of Takase’s flow paths can be              
          the same as those of the appellants’ and Cottingham’s                       
          microchannels, and the lowest exemplified width of Takase’s flow            
          paths is comparable to the appellants’ preferred microchannel               


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