Ex Parte MIAN et al - Page 8




          Appeal No. 2004-0615                                                        
          Application No. 08/761,063                                                  

          width and is not limited, it reasonably appears that Takase                 
          discloses, or would have fairly suggested, to one of ordinary               
          skill in the art, microchannels as Takase’s flow paths.                     
               The appellants argue that Takase’s maximum disclosed disk              
          rotation speed is approximately 3,000 rpm (col. 7, lines 17-18)             
          and that at the high speeds required to drive fluid through                 
          microchannels, Takase’s fluid would be displaced from Takase’s              
          open flow paths (brief, pages 13-14).  This argument is not well            
          taken because, first, the appellants disclose that fluid can be             
          driven through microchannels using a disk rotation speed as low             
          as 1 rpm (specification, page 5, lines 10-11).  Second, the fluid           
          displacement problem suggested by the appellants clearly would              
          not exist when Cottingham’s top film 72 is applied over Takase’s            
          flow paths.                                                                 
               The appellants argue that placing Cottingham’s top film over           
          Takase’s flow paths may interfere with the supply means (brief,             
          page 14).  Like Cottingham (col. 8, lines 26-28), one of ordinary           
          skill in the art would leave a hole in the top film for a sample            
          port.                                                                       
               The appellants argue that Cottingham’s top film may                    
          interfere with Takase’s measuring head 11 (brief, page 14), but             
          do not provide any support for this argument.  Takase’s measuring           


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