Ex Parte Rubin et al - Page 2




               Appeal No. 2004-1106                                                                   July 2004                       
               Application 09/871,388                                                                 Page 2                          
               rejection of claims 14-21 and 23-33.  Claim 22, the only other claim pending in this                                   
               application, has been indicated as allowable.3  We affirm.                                                             
                       Claims 14-21 and 23-33 stand rejected under 35 U.S.C. § 112, first paragraph,                                  
               as lacking original descriptive support.                                                                               
                       In reaching our decision in this appeal, we have given careful consideration to                                
               the appellants' specification and claims and to the respective positions articulated by                                
               the appellants and the examiner.  We make reference to the EXAMINER'S ANSWER                                           
               ("Answer," mailed 6 August 2003) for the examiner's reasoning in support of the                                        
               rejection and to appellant's BRIEF ON APPEAL ("Brief," filed 12 May 2003) and REPLY                                    
               BRIEF ON APPEAL ("Reply," filed 22 September 2003) for appellants' arguments                                           
               thereagainst.                                                                                                          
                       Appellants state "all the claims stand as a group" (Brief, p. 2).  We, therefore,                              
               limit our discussion to claim 14.  37 CFR § 1.192(c)(7).                                                               
               II.     Findings of fact                                                                                               
                       The following facts are supported by a preponderance of the evidence.                                          
                       A.      KUZ and MADM proteins                                                                                  
               1.      According to appellants' specification, KUZ  refers to a family of proteins                                    
               encoded by a "new" gene family kuzbanian (kuz) which belong to the recently defined                                    
               ADAM family of transmembrane proteins, members of which contain both A Disintegrin                                     
               And Metalloprotease domains (p. 2, ll. 6-13).4                                                                         

                       3 See e.g., Final Office Action (issued 11 March 2003, Paper 10), p. 2.                                        
                       4 Italics are used herein to refer to a gene, whereas capitals are used to refer to a protein.  Thus,          





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