Ex Parte Rubin et al - Page 7




               Appeal No. 2004-1106                                                                   July 2004                       
               Application 09/871,388                                                                 Page 7                          
               III.    Opinion                                                                                                        
                       A.      The legal standard                                                                                     
                       "The test for determining compliance with the written description requirement is                               
               whether the disclosure of the application as originally filed reasonably conveys to the                                
               artisan that the inventor had possession at that time of the later claimed subject matter,                             
               rather than the presence or absence of literal support in the specification for the claim                              
               language."  In re Kaslow, 707 F.2d 1366, 1375, 217 USPQ 1089, 1096 (Fed. Cir. 1983).                                   
               The written description requirement can be satisfied by showing that the disclosed                                     
               subject matter, when given its "necessary and only reasonable construction," inherently                                
               (i.e., necessarily) satisfies the limitation in question.  Kennecott v. Kyocera, 835 F.2d                              
               1419, 1423, 5 USPQ2d 1194, 1198 (Fed. Cir. 1987).                                                                      
                       B.      Appellants' position                                                                                   
                       Appellants contend that support for an antibody or fragment thereof which                                      
               specifically binds one of the recited KUZ proteins but does not specifically bind bovine                               
               MADM can be found at page 5, lines 20-24, 28-29 and 29-31 and at page 8, line 18                                       
               through page 10, line 8 (FF 14).                                                                                       
               20.     Specification pages 8 through 10 describe adapting known techniques of                                         
               producing antibodies or antibody fragments to a generic antigen to production of                                       
               antibodies or antibody fragments to a specific antigen, i.e., a KUZ protein, derivative or                             
               analog (p. 8, ll. 18-19 and 31-32).                                                                                    
               21.     As noted by the examiner, there is no disclosure of antibodies which specifically                              
               bind to the protein defined by any of SEQ ID NOS 2, 4, 6 and 8 but not to MADM                                         






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