Interference 103,781
Q. One of the sequences listed is the ATTTA sequence,
about halfway down in that page; isn’t that true, sir?
A. Yes.
Q. As of April 25th, 1988, is it correct that you
considered the ATTTA sequence to be one of the nasties
because it was potentially destabilizing?
. . . . .
A. Yes.
Dr. Adang’s certainty in April 1988 is in marked contrast
to his uncertainty that the ATTTA sequence was destabilizing
messenger RNA on September 26, 1986, which we quote again
(AR 0372):
Q. And the reason you performed the search was
because you believed at the time that the ATTTA sequence
was potentially a destabilizing sequence in the Bt gene
that interfered with expression of the Bt gene in plants;
correct?
A. Yes. With, you know, emphasis on the term
“potentially,” yeah. Yes.
Relative to his view of the cause of mRNA instability at the end
of 1986, Dr. Adang testified (AR 0374)(emphasis added), “As a
consequence of my awareness of Shaw Kamen sequences and awareness
of the presence in Bt genes, I considered that these sequences
may have a destabilizing effect on Bt messenger RNA . . . .”
The evidence as a whole shows that Drs. Adang and Murray
identified many other potential causes for premature termination
of transcription and inefficient expression of Bt genes encoding
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