BAI et al v. LAIKO et al - Page 51




                Interference No. 104,745                                                                                                      

                However, Dr. Burlingame did not explain when these other lasers were made available to                                        
                Talrose and Fred, which leaves open the possibility that they were not obtained until after the                               
                broken laser was repaired by Laser Science and returned to UCSF in February 1998.                                             
                         For the foregoing reasons, we hold that it was reasonable for Laiko to decide to obtain an                           
                estimate of the cost of repairing the laser, with the result that Dr. Baldwin's 26 November 1997                              
                repair inquiry to Laser Science and the subsequent shipment of the laser from UCSF to the Laser                               
                Science facility (located in Massachusetts), which necessarily occurred prior to Laser Science's                              
                19 December 1997 repair estimate, are sufficient to establish that reasonable diligence toward an                             
                actual reduction to practice of the AP-MALDI invention began just prior to Bai's 19 December                                  
                1997 conception date.                                                                                                         
                         Inasmuch as 19 December was a Friday, Dr. Burlingame's above-noted e-mail to Dr.                                     
                Baldwin on 23 December (Tuesday) authorizing the laser repair was reasonably prompt.30  The                                   
                UCSF Mass Spectrometry Facility was closed on 24 December (Wednesday), 25 December                                            
                (Thursday),  27 December (Saturday), 28 December (Sunday), 31 December  (Wednesday), and                                      
                1 January (Thursday).  Baldwin Decl. (LX 1074) ¶ 52.  In addition, Dr. Baldwin, to whom Dr.                                   
                Burlingame's authorization to proceed with laser repair apparently was directed, did not work on                              
                26 December, the British holiday of "Boxing Day."  Baldwin Depo., LR 290, ll. 11-14.  Under                                   
                these circumstances,  it was reasonable for Dr. Baldwin to wait until 2 January (Friday) to                                   


                30  Dr. Burlingame's testimony that he "would be amazed" if Ms. Schwartz did not forward the                                  
                approval to Laser Science on 23 December, Burlingame Depo., LR 400, l. 17 to LR 401, l. 9, is                                 
                unsupported by her declaration testimony (LX 1062) and contradicted by Denny's testimony,                                     
                both discussed infra.                                                                                                         
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