Ex Parte LEE et al - Page 7




             Appeal No. 2003-2147                                                                              
             Application No. 09/392,243                                                                        
             referencing use of calcium propionate, BHT, and BHA as alternatively acceptable                   
             preservatives...”  Brief, page 13.  Appellants argue that “[t]he Van Gorp patent suggests         
             the use of oxygen scavengers as preservatives.  The Van Gorp patent does not suggest              
             the incorporation of either an oxidizer (such as hydrogen peroxide) or an acidifier (such         
             as phosphoric acid) in the process disclosed in the Van Gorp patent.”  Brief, page 14.            
                   In addition, appellants provide evidence, Exhibit D, Jay, James M.,  Modern Food            
             Microbiology, pages 259-296 (1986), which according to appellants, demonstrates there             
             is no support for the position that the Oles phosphoric acid “would have functioned               
             equivalently to the preservatives disclosed by Van Gorp...”  Brief, page 14.                      
                   Appellants argue that Oles relies on a synergistic combination of acidifying                
             agents (a combination of (1) acetic acid or other organic acid and (2) phosphoric acid),          
             whereas the Van Gorp patent principally relies on an oxygen scavenging stabilizer ...             
             [and] demonstrates the wide difference in operating function between the preservatives            
             of the Van Gorp patent and the preservatives of the Oles patent.  Brief, page 14.                 
                   Finally, appellants argue that Balslev “actually teaches away from using                    
             hydrogen peroxide as a preservative in the process disclosed in the Van Gorp patent.              
             The Van Gorp patent principally teaches preservation by scavenging oxygen from the                
             mucosa tissue with oxygen scavengers. ...  According to the Balslev patent the                    
             hydrogen peroxide serves an oxidizing bactericide. ... An oxidizing agent provides                
             oxygen to an active site via a chemical reaction.  Providing oxygen to mucosa tissue is           
             exactly the opposite result of that desired by the preservatives principally employed in          

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