Ex Parte Polonsky et al - Page 16


                     Appeal No.  2005-0258                                                                          Page 16                        
                     Application No.  09/768,877                                                                                                   
                     describe the genus by describing a “representative number” of calpain 10                                                      
                     polypeptides, wherein the representative species are described according to the                                               
                     standard of either Lilly or Enzo.  Since the specification does not adequately                                                
                     describe the calpain 10 polypeptides required to practice the method of claim 51,                                             
                     it does not adequately describe the claimed method.                                                                           
                              For the foregoing reasons, we affirm the rejection of claim 51 under the                                             
                     written description provision of 35 U.S.C. § 112, first paragraph.  As discussed                                              
                     supra claims 18-21, 49, 50, 53-64, 115 and 116 fall together with claim 51.                                                   


                     Enablement:                                                                                                                   
                              Claims 18-21, 49-51, 53-64, 115 and 116 stand rejected under 35 U.S.C.                                               
                     § 112, first paragraph, as based on an insufficient disclosure to support or enable                                           
                     the scope of the claimed invention.  Having disposed of all claims on appeal as                                               
                     unpatentable over the written description provision of 35 U.S.C. § 112, first                                                 
                     paragraph, we do not reach the merits of the rejection under the enablement                                                   
                     provision of 35 U.S.C. § 112, first paragraph.                                                                                



















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