Ex Parte Liu et al - Page 4


               Appeal No. 2005-0295                                                                                                  
               Application 10/151,586                                                                                                

                       We find that Abdel-Malik would have disclosed to one of ordinary skill in this art1 blends                    
               of plasticized proteinaceous material in which a plasticizer is selectively matched with a protein                    
               such that the plasticizer can be uniformly distributed within the protein, and the blends used in                     
               the production of gum (e.g., abstract, and col. 4, ll. 14-41).  Abdel-Malik would have further                        
               disclosed that matching a plasticizer with a protein can be “accomplished in part by matching the                     
               solubility parameters of the protein . . . and plasticizer . . . within a desired range . . . are                     
               determined by their relative cohesive properties,” wherein the “solubility parameter . . . is the                     
               sum of the solubility parameter values contributed by dispersive forces, hydrogen bonding forces                      
               and polar forces” (col. 6, l. 61, to col. 7, l. 16).  Thus, “a protein will dissolve in a plasticizer or              
               be plasticized if either the total solubility parameter . . . or one or more of said disperse forces[,]               
               . . . polar forces . . . and hydrogen bonding forces . . . for each of the protein and plasticizer are                
               similar,” that is, “if any one or more of the . . . solubility parameter values for a protein and                     
               plasticizer or respective mixtures thereof are within 15% of each, preferably 10%, the protein . . .                  
               and the plasticizer . . . may present a potential blend suitable for making the plasticized                           
               proteinaceous material” (col. 7, ll. 17-67).                                                                          
                       In Abdel-Malik Table 1, the total solubility parameter, the disperse forces, polar forces                     
               and hydrogen bonding forces of zein, a corn protein, and of the listed carbon compound                                
               plasticizers as well as water as a plasticizer are listed (col. 8, and col. 11, l. 40).  We find that one             
               of ordinary skill in the art routinely following the teachings of the reference would have matched                    
               at least one of the solubility parameters for the carbon compound plasticizer within 15% of at                        
               least one of the solubility parameters for zein, thus arriving at suitable blends of the two                          
               ingredients for the preparation of plasticized proteinaceous materials such as a gum base and                         
               gum (col. 8, ll. 9-45).  Indeed, blends of zein with listed isopropyl alcohol and isobutyl alcohol                    
               are particularly noted in this respect (col. 8, ll. 34-40).  The reference teaches that further                       
               screening of the blends is optional (col. 8, ll. 48-52).                                                              
                                                                                                                                    
               1 It is well settled that a reference stands for all of the specific teachings thereof as well as the                 
               inferences one of ordinary skill in this art would have reasonably been expected to draw                              
               therefrom, see In re Fritch, 972 F.2d 1260, 1264-65, 23 USPQ2d 1780, 1782-83 (Fed. Cir.                               
               1992); In re Preda, 401 F.2d 825, 826, 159 USPQ 342, 344 (CCPA 1968); In re Aller, 220 F.2d                           
               454, 458-59, 105 USPQ 233, 237 (CCPA 1955), presuming skill on the part of this person.  In re                        
               Sovish, 769 F.2d 738, 743, 226 USPQ 771, 774 (Fed. Cir. 1985).                                                        

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