Ex Parte Knebel et al - Page 3



          Appeal No. 2005-0510                                                        
          Application No. 09/883,435                                                  

          54 under section 103(a) over Kim essentially for the reasons stated         
          in the Answer and those reasons set forth below.  We reverse the            
          rejection of claims 27-29, 36 and 38 under section 103(a) over Kim          
          for reasons which follow.  Accordingly, the decision of the                 
          examiner is affirmed-in-part.                                               
          OPINION                                                                     
               The examiner finds that Kim discloses a crystallization tray           
          housing where each tray has a plurality of separate crystallization         
          units, with each unit consisting of a reservoir, a drop chamber             
          with a shoulder for placement of a cover slip, and a cover slip             
          from which a drop solution for crystal growth can be suspended              
          (Answer, page 3).  The examiner also finds that Kim teaches                 
          optimization of the geometry of the drop chamber (id., citing col.          
          6, ll. 8-24).  From these findings, the examiner concludes that it          
          would have been obvious to one of ordinary skill in this art at the         
          time of appellants’ invention to design the reaction vessel with            
          respect to size and shape of the recesses and reaction areas, as            
          well as the number of reaction areas in the vessel (Answer, page            
          4).                                                                         
               Appellants argue that Kim discloses that each drop chamber 32          
          is outside the central reservoir 28, and the central reaction               

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