Ex Parte Knebel et al - Page 9



          Appeal No. 2005-0510                                                        
          Application No. 09/883,435                                                  

          ordinary skill in this art at the time of appellants’ invention to          
          use well known geometric forms for the reaction chamber.                    
               For the foregoing reasons and those stated in the Answer, we           
          determine that the examiner has established a prima facie case of           
          obviousness in view of the reference evidence.  Based on the                
          totality of the record, including due consideration of appellants’          
          arguments, we determine that the preponderance of the evidence              
          weighs in favor of obviousness within the meaning of section                
          103(a).  Accordingly, we affirm the examiner’s rejection of claims          
          1-3, 6-10, 12-24, 30-35, 53 and 54 under 35 U.S.C. § 103(a) over            
          Kim.                                                                        
               Appellants argue that nothing in Kim suggests another reaction         
          area formed by a recess above the reservoir as recited in claims 36         
          and further limited in claim 27 (Brief, page 13; Reply Brief, page          
          2).  The examiner concludes that it would have been obvious to one          
          of ordinary skill in the art “to include a top part or lid with a           
          reaction area (see col. 2 lines 63 and col. 3 lines 1-5) since Kim          
          discloses such.”  Answer, page 4.  The examiner finds that Kim              
          discloses “a lid (i.e., a cover slip) with a reaction area (see             
          col. 2 lines 63 and col. 3 lines 1-5).”  Answer, page 5.                    
               We agree with the examiner’s findings but note that all of the         
          claimed limitations have not been disclosed or suggested by these           
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