Appeal No. 2005-0545 Application No. 09/989,019 Moreover, genistein is not representative of all the alternative isoflavones of Pugliese’s claims. Note that genistein is four times the PDE inhibitor that its alternative daidzein is (Kuppusamy, p. 1309, Table 2). Accordingly, Pugliese showing is not commensurate in scope with the scope of the compositions and methods claimed. “[O]bjective evidence of nonobviousness must be commensurate in scope with the claims.” In re Kulling, 897 F.2d 1147, 1149, 14 USPQ2d 1056, 1058 (Fed. Cir. 1990). We have considered all the evidence and arguments favoring patentability and all the evidence and arguments to the contrary. In our view, the examiner’s case for unpatentability of the claimed subject matter under 35 U.S.C. § 103 is supported by the greater weight of all the evidence. Accordingly, we affirm the examiner’s final rejection of Claims 1-7 and 9-11 of Application 09/989,019 under 35 U.S.C. § 103 in view of the combined teachings of Soudant, Koulbanis, Majeed, Sekiya, De Simone, Lotte, Kuppusamy, and Gennaro. AFFIRMED. New Ground of Rejection Under 37 CFR § 41.50(b) THIS IS A NEW GROUND OF REJECTION. Method Claim 8 of Application 09/989,019 is hereby rejected anew under 35 U.S.C. § 103 in view of the combined teachings of Soudant, Koulbanis, Majeed, Sekiya, De Simone, Lotte, Kuppusamy, and Gennaro. In the 23Page: Previous 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 NextLast modified: November 3, 2007