Appeal No. 2005-0102 Page 3
Application No. 09/840,787
parathyroid, penis, prostate, salivary glands, skin, spleen, testis, thymus,
thyroid, and uterus.
Page 38.
In addition to therapy, the specification states that
[p]olynucleotides encoding HRM may be used for the diagnosis of
conditions, disorders, or diseases which are associated with either
increased or decreased expression of HRM. Examples of such conditions
or diseases include adenocarcinoma, leukemia, lymphoma, melanoma,
myeloma, sarcoma, teratocarcinoma, and cancers of the adrenal gland,
bladder, bone, brain, breast, cervix, gall bladder, ganglia, gastrointestinal
tract, heart, kidney, liver, lung, bone marrow, muscle, ovary, pancreas,
parathyroid, penis, prostate, salivary glands, skin, spleen, testis, thymus,
thyroid, and uterus; and immune disorders such as AIDS, Addison’s
disease, adult respiratory distress syndrome, allergies, anemia, asthma,
atherosclerosis, bronchitis, cholecystit[i]s, Crohn’s disease, ulcerative
colitis, atopic dermatitis, dermatomyositis, diabetes mellitus, emphysema,
atrophic gastritis, glomerulonephritis, gout, Graves’ disease,
hypereosinophilia, irritable bowel syndrome, lupus erythematosus, multiple
sclerosis, myasthenia gravis, myocardial or pericardial inflammation,
osteoarthritis, osteoporosis, pancreatitis, polymyositis, rheumatoid
arthritis, scleroderma, Sjögren’s syndrome, and thyroiditis.
Pages 47-48.
Discussion
1. Claim construction
Claims 2-14 and 21 are pending and on appeal. The claims stand or fall
together. Appeal Brief, page 3. We will focus on claim 2, which reads as follows:
2. An isolated polynucleotide comprising a nucleic acid sequence encoding a
protein having the amino acid sequence of SEQ ID NO:19 or the complete
complement of the polynucleotide.
Thus, claim 2 is directed to a polynucleotide (RNA or DNA) that comprises a
nucleotide sequence encoding the amino acid sequence shown in the specification’s
SEQ ID NO:19, or a complete complement of such a polynucleotide.
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