Ex Parte Beutler et al - Page 16


              Appeal No. 2006-0227                                                                  Page 16                 
              Application No. 10/121,264                                                                                    

              different container or taken up in a pipette, it would transport the chromosomal DNA                          
              along with it.                                                                                                
                     The upturned Falcon tube cap meets the specification’s definition of a substrate                       
              (“an object onto which genetic material may be deposited”) that comprises a matrix (“a                        
              material that includes transfer agent spaces”; specifically, the plastic that the cap is                      
              made of) and a transfer agent space (“a region capable of containing at least one                             
              transfer agent”; specifically, the concave area inside the upturned cap, which is capable                     
              of containing the sucrose solution).  Thus, claim 24 reads on the microcentrifugation                         
              chamber disclosed by Kausch.                                                                                  
                     Appellants argue that “the sucrose in Kausch that the Examiner alleges is a                            
              transfer agent layer does not meet the definition of a transfer agent layer presented in                      
              Appellants’ specification.  Kausch uses sucrose as a physical cushion for a coverslip, to                     
              prevent the coverslip from breaking during centrifugation.  The sucrose itself never                          
              moves independent of the coverslip, and does not transport genetic material anywhere.”                        
              Appeal Brief, page 28.                                                                                        
                     We disagree with Appellants’ interpretation of the claim.  The specification                           
              defines a transfer agent layer as a layer comprising “a substance onto or into which                          
              genetic material may be deposited, which can transport the genetic material when the                          
              [substance] is moved.”  Specification, page 13.  A solution of 1M sucrose (or any other                       
              liquid, for that matter) is capable of having genetic material deposited into it, and of                      
              transporting the genetic material when the solution is moved.  Thus, a one centimeter                         
              deep layer of 1M sucrose meets the specification’s definition of a transfer agent layer.                      
              The fact that the solution was not actually used to transport chromosomes from one                            





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