Ex Parte Wolf - Page 3


                Appeal No. 2006-2467                                                  Page 3                 
                Application No. 10/157,644                                                                   

                relatively stable blood sugar levels . . . for up to six to nine hours,” and is              
                “administered in place of, or as part of the evening snack or as a daytime snack.”           
                Id.  (emphasis removed).  Kaufman is also relied upon for teaching that                      
                “administration depends on patient parameters such as weight, age, and                       
                condition of the patient such as whether the patient takes insulin or other                  
                antidiabetic medications, and the blood sugar profile determined by a finger                 
                stick.”  Id. at 4.  The examiner notes that “Kaufman [ ] does not specify the instant        
                time period or the instant form of fructose.”  Id.                                           
                      Anderson is relied upon for teaching the use of fructose supplements in                
                various forms, such as lemonade-flavored drinks, cookies, or crystalline fructose.           
                See id.  Anderson is also relied upon for teaching that “fructose supplements                
                improve the glycemic response in diabetic and non-diabetic patients.”  Id.                   
                      The examiner concludes that it                                                         
                      would have been obvious to one of ordinary skill in the art at the                     
                      time the invention was made to administer Kaufman’s food                               
                      composition within the instant time frame since Kaufman teaches                        
                      that the composition is utilized to maintain the blood sugar level and                 
                      administration and amount administered depends on an array of                          
                      factors such as weight, age, and the condition of the patient such                     
                      as whether the patient takes insulin or other antidiabetic                             
                      medications, and the blood sugar profile determined by a finger                        
                      stick.  For instance, one would have been motivated to consume                         
                      Kauffman’s therapeutic composition prior to a meal, if one’s blood                     
                      sugar profile was near hypoglycemia (low blood sugar level) and                        
                      the time in which the next meal is consumed depends on the blood                       
                      sugar level since a meal immediately consumed with the fructose                        
                      source may cause hyperglycemia.  Therefore, the time frame in                          

                                                                                                             
                4 Moore et al. (Moore), “Acute Fructose Administration Decreases the Glycemic Response to an 
                Oral Glucose Tolerance Test in Normal Adults,” The Journal of Clinical Endocrinology &       
                Metabolism, Vol. 85, pp. 4515-19 (2000).                                                     





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