Ex Parte Bianchi et al - Page 2


            Appeal No. 2006-2546                                                          Page 2              
            Application No. 10/425,177                                                                        

            0.5 grams per 100 ml of solvent, a molecular weight in a range of between about 1 and             
            500 kilodaltons and a weight/weight ratio of polymer to solvent in a range between                
            about 0.5:100 to 100:0.5.”  Page 2, lines 21-24.  “[T]he composition is liquid in a solvent       
            and undergoes a gel transition inside a target breast milk duct within about 30 minutes           
            of delivery of the composition to the target duct.”  Page 2, lines 24-26.                         
                   The specification states that the polymer can comprise, for example, polyvinyl             
            alcohol, polyvinyl pyrrolidone, polyalkylene glycols, or polyethylene oxide.  Page 6,             
            line 32, to page 7, line 5.  In the Examples, the specification describes using                   
            PLURONIC® F-127.  Page 28, line 21.                                                               
                   The gel can “comprise an additive to provide detection of the gel inside the target        
            duct. . . . The additive can be a dye.”  Page 3, lines 17-20.  “The additive can provide          
            visual detection of the gel by the naked eye, or can be an additive that is capable of            
            detection by a special sensor or machine or other mechanism that is sensitive to the              
            presence of such an additive and which can detect material that has the additive and              
            distinguish such material from other material not containing the particular additive.”            
            Page 14, lines 15-19.                                                                             
                                                 Discussion                                                   
            1.  Claim construction                                                                            
                   Claims 10-13 and 16-22 are pending and on appeal.  We will focus on claim 10,              
            the broadest claim on appeal, which reads as follows:                                             
                   10. A biocompatible composition comprising a polymer that has a                            
                         solubility greater than 0.5 grams per 100 ml of solvent, a molecular                 
                         weight in a range of between about 1 and 500 kilodaltons and a                       
                         weight/weight ratio of polymer to solvent in a range of between                      
                         about 0.5:100 to 100:0.5, wherein the composition is a liquid in a                   





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