Ex Parte Bianchi et al - Page 5


            Appeal No. 2006-2546                                                          Page 5              
            Application No. 10/425,177                                                                        

            phrase limits the additive to an additive that is capable of providing detection of the gel       
            inside a breast milk duct.                                                                        
                   The examiner has not adequately explained how any of the additives described               
            in Krezanoski would be capable of providing detection of the gel inside a breast milk             
            duct.  Thus, we agree with Appellants that the examiner has not set forth a prima facie           
            case that Krezanoski anticipates claim 10.  We therefore reverse the rejection of                 
            claims 10 and 16-21 under 35 U.S.C. § 102(b) over Krezanoski.                                     
            3.  Snow                                                                                          
                   The examiner rejected claims 10-13, 17-19, 21, and 22 under 35 U.S.C. § 102(e)             
            as anticipated by Snow.2  The examiner argued that “Snow discloses [a] pharmaceutical             
            composition comprising [a] physiologically tolerable contrast agent that contains at least        
            two chromophores and at least one polyalkylene oxide moiety (column 9, lines 1-12).”              
            Examiner’s Answer, page 4.  “[I]n one embodiment the chromophoric group is attached               
            to a surfactant molecule (column 9, lines 13-15).  The surfactant is disclosed to be              
            polyalkyleneoxide block copolymer that may be branched (column 9, lines 52-57);                   
            PLURONIC and TETRONIC block copolymers are used with the chromophores                             
            (column 10, lines 35-44).”  Id.  The examiner argued that “[t]he chromophores of                  
            Snow . . . would provide detection of the gel inside the target breast milk duct.”  Id.,          
            page 6.  In addition, the examiner argued that Snow, at column 54, lines 11-21,                   
            contemplates administering the composition as an aqueous solution or suspension.  Id.,            
            page 8.                                                                                           

                                                                                                              
            2 Snow et al., U.S. Patent No. 6,350,431, issued February 26, 2002, from an application filed October 28,
            1999.                                                                                             





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