Ex Parte Bianchi et al - Page 3


            Appeal No. 2006-2546                                                          Page 3              
            Application No. 10/425,177                                                                        

                         solvent and undergoes a gel transition inside a target breast milk                   
                         duct within about 30 minutes of delivery of the composition to the                   
                         target duct, and further comprises an additive to provide detection                  
                         of the gel inside the target breast milk duct.                                       
                   Thus, claim 10 is directed to a biocompatible composition that contains a polymer          
            with a solubility, molecular weight, and weight ratio of polymer to solvent within specified      
            ranges.  In addition, claim 10 recites that the composition is a liquid in a solvent and          
            undergoes a gel transition inside a target breast milk duct within about 30 minutes of its        
            delivery to the duct.                                                                             
                   Claim 10 also recites that the composition contains “an additive to provide                
            detection of the gel inside the target breast milk duct.”  “[The additive can provide visual      
            detection of the gel by the naked eye, or can be an additive that is capable of detection         
            by a special sensor or machine or other mechanism.”  Specification, page 14, lines 15-            
            19.  Thus, we interpret the claim to require an additive that is capable of providing             
            detection of the gel inside a breast milk duct; e.g., by visual detection or by using a           
            special sensor, machine, or other mechanism.                                                      
            2.  Krezanoski                                                                                    
                   The examiner rejected claims 10 and 16-21 under 35 U.S.C. § 102(b) as                      
            anticipated by Krezanoski.1  The examiner argued that:                                            
                   Krezanoski discloses a liquid composition comprising polyoxyethylene-                      
                   polypropylene block copolymer wherein the composition has a sol-gel                        
                   transition temperature in the range from about 25 °C to about 40 °C; the                   
                   polymer has a molecular weight of 7,500 Daltons to about 15,500 Daltons                    
                   and the solubility is greater than about 10 gram[s] per 100 ml water                       
                   (abstract, column 2, line 64 to column 3 and line 19, column 5, lines 28-33                
                   and Examples I-VIII).                                                                      

                                                                                                              
            1 Krezanoski, U.S. Patent No. 4,188,373, issued February 12, 1980.                                





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