Appeal No. 2006-0647
Application No. 10/069,561
and “[t]he degree of substitution . . . is such as to render the corresponding
carboxyalkyl-cellulose soluble in water, . . . said degree of substitution is . . .
between 0.4 and 1.5” (id. at col. 2, ll. 21-29). “After removal of the
[organic] diluent, the carboxyalkyl-cellulose . . . is subjected to a heat-
treatment . . . so as to achieve the internal cross-linking of the carboxyalkyl-
cellulose, and thus make it practically insoluble in water” (id. at col. 2, ll.
62-68). Colombo’s insoluble, absorbent “cellulosic products . . . are
particularly suitable for use in sanitary towels or napkins, bandages,
tampons, and the like” (id. at col. 6, l. 67 to col. 7, l. 2).
Edwardson describes a method of making non-crosslinked fibrin
monomers or polymers by passing plasma over a thrombin-like enzyme
immobilized on a solid support, which can be made from a number of
materials, including cellulose (Edwardson col. 8, l. 67 to col. 9, l. 35).
Sugitachi describes “a wound healing material capable of effectively
promoting the formation of stabilized fibrin at a wound site . . . for a long
period of time” (Sugitachi col. 1, ll. 39-45). The wound healing material
comprises a structure, wherein “[t]he term ‘structure’ . . . refers to all
conventional materials used in healing a wound site, which may have
various forms such as monofilaments; fibrous assemblies, such as cotton,
paper, non-woven fabrics, woven fabrics, and knitted fabrics; films;
sponges; etc.” (id. at col. 1, ll. 49-55). “Examples of the materials which
make up such structures [include] . . . [c]ellulose, viscose rayon,
cupraammonium rayon, cellulose acetate, carboxymethyl cellulose, methyl
cellulose,” etc. (id. at col. 1, l. 64 to col. 2, l. 1).
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