Ex Parte Termin et al - Page 3

                 Appeal No. 2006-2573                                                                                
                 Application No. 10/192,055                                                                          

                        reference compounds and the formulations thereof.  The                                       
                        preamble is not given any patentable weight as it merely recites                             
                        an intended use.                                                                             
                 Id. at 4-5.                                                                                         
                        “In rejecting claims under 35 U.S.C. § 103, the examiner bears the                           
                 initial burden of presenting a prima facie case of obviousness.  Only if that                       
                 burden is met, does the burden of coming forward with evidence or                                   
                 argument shift to the applicant.”  In re Rijckaert, 9 F.3d 1531, 1532, 28                           
                 USPQ2d 1955, 1956 (Fed. Cir. 1993) (citations omitted).  The test of                                
                 obviousness is “whether the teachings of the prior art, taken as a whole,                           
                 would have made obvious the claimed invention.”  In re Gorman, 933 F.2d                             
                 982, 986, 18 USPQ2d 1885, 1888 (Fed. Cir. 1991).                                                    
                        Appellants argue that of all of the 338 compounds exemplified by                             
                 Kasahara, only a single species, II-36, as the r1 and r2 forming the                                
                 cyclopropyl, and that species has been removed from claim 1 by proviso (Br.                         
                 9).  Appellants assert “there is no overlap, and so no prima facie case of                          
                 obviousness was made.”  Id.  Thus, in order to arrive at the claimed                                
                 compounds, appellants assert that “[a] large number a variables must be                             
                 selected or modified with no guidance from the reference.”  Id.  We do not                          
                 find Appellants’ arguments to be convincing, and the rejection is affirmed.                         
                        Appellants are claiming a large genus of compounds, which appears                            
                 to be a subgenus of the larger prior art genus of Kasahara.  Kasahara                               
                 specifically disclosed only one species, compound II-36, that fell within                           
                 Appellants’ genus, and disclosed that it has fungicidal activity against apple                      
                 scab (Example 6, page 73, Table 15, page 76).                                                       


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