Ex Parte Termin et al - Page 4

                 Appeal No. 2006-2573                                                                                
                 Application No. 10/192,055                                                                          

                        Admittedly, the claim excludes that species, as it has been carved out                       
                 by proviso.  However, the claims do not exclude obvious variants of that                            
                 compound, such as a compound having a bromo rather than a chloro on the                             
                 phenyl ring, or a compound in which ethyl has been substituted for methyl                           
                 on the pyridinyl ring.                                                                              
                        As noted by the examiner,                                                                    
                              the reference teaches a genus (see formula (b) in page 31                              
                        of the translation papers) and a species that falls within the                               
                        genus (see Table 2, compound II-36, the structural formulae of                               
                        the genus and species are depicted below for convenience):                                   




                        The instant claims exclude a small subgenus, that includes the                               
                        reference disclosed compound, from the claims, see the proviso                               
                        statement.  The reference however, teaches the functional                                    
                        equivalency of the substituent groups to be alternatives. . . . .                            
                        Therefore, the reference teaches the equivalency of methyl,                                  
                        ethyl, chloro, fluoro, etc. as all these are taught as alternatives                          
                        of the ring substituents and thus, the reference clearly suggests                            
                        compounds that fall within the genus of instant compounds.                                   
                        The necessary motivation to make the structurally analogous                                  
                        compounds of the reference rises from the expectation that                                   
                        compounds, similar in structure will have similar properties and                             
                        therefor, the same use, i.e., as fungicides.                                                 
                              Appellant[s] cite[ ] MPEP § 2144.08 and argue[] that ‘a                                
                        large number of variables must be selected or modified with no                               
                        guidance from the reference—the similar structures were                                      
                        already removed by proviso’.  This is not found to be                                        
                        persuasive because one of ordinary skill in the art need to select                           
                        or modify only one of the substituent groups to arrive at the                                
                        instantly claimed compounds, e.g., 2-ethyl in place of the 2-                                

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