Ex Parte Barrett et al - Page 14

                Appeal 2006-3020                                                                                   
                Application 10/109,374                                                                             
                The Second Issue:  35 U.S.C. § 112, ¶ 2                                                            
                       Likewise, we conclude claim 39, defined by both function and                                
                structure, particularly points out and distinctly claims the subject matter                        
                Appellants regard as their invention.  The Examiner’s bases for concluding                         
                otherwise appear to rest on the functional language and breadth of claim 39.                       
                However, the law is quite settled on these points:  Neither the use of                             
                functional language nor claim breadth violates the second paragraph of                             
                § 112.  To affirm a rejection under this statutory provision, we must                              
                conclude the “language used is not precise and definite enough to provide a                        
                clear-cut indication of the scope of subject matter embraced by the claim.”                        
                Swinehart, 439 F.2d at 213, 169 USPQ at 229.  In this case, we cannot draw                         
                such a conclusion and thus reverse the § 112, ¶ 2 rejection.                                       
                The Third Issue:  35 U.S.C. § 103(a)                                                               
                       With respect to the third issue before us, we find Dunn’s teaching that                     
                chelator-derivatized biomolecules, including receptor binding molecules,                           
                can be used to deliver diagnostic or therapeutic agents to a target, would                         
                have motivated the skilled artisan to derivatize Dereu’s LTB4 receptor                             
                binding moieties, with a reasonable expectation of success.  Thus, we                              
                conclude the invention of claim 39 would have been obvious to one of                               
                ordinary skill in the art at the time the invention was made.                                      
                       Appellants argue “there is no teaching or suggestion on how to                              
                combine a LTB4 binding moiety with a chelator.”  (Br. 10.)  However, based                         
                on Dunn’s teachings and Appellants’ own admissions, no such teaching or                            
                suggestion is needed for the skilled artisan to have a reasonable expectation                      
                of success.  (See Dunn, col. 5, ll. 34-36 (“Coupling of the chelating moieties                     
                to biomolecules can be accomplished by several known methods.”);  Spec.                            

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