Ex Parte Esser et al - Page 20


                Appeal 2006-3252                                                                                 
                Application 09/536,728                                                                           

                                                           H                                                     
                                                           N                                                     
                                              R    N                                                             
                                                             N                                                   
           1                                                 H                                                   
           2                                      Formula 10                                                     
           3    where R is limited to the Markush Group:                                                         
           4           (1)  2,6-dichloro-4-hydroxymethyl-phenyl;                                                 
           5           (2)  2-chloro-4-methyl-5-amino-phenyl (the compound of Formula 7,                         
           6    supra);                                                                                          
           7           (3) 2,5-dichloro-4-methyl-phenyl;                                                         
           8           (4) 2-chloro-4-methyl-5-nitro-phenyl;                                                     
           9           (5)  2,3-dichloro-4-methyl-phenyl;                                                        
          10           (6)  2-chloro-4-methyl-6-nitro-phenyl;                                                    
          11           (7)  2-chloro-4-methyl-6-amino-phenyl;                                                    
          12           (8)  2,4,6-trifluorophenyl;                                                               
          13           (9)  tetrafluorophenyl; or                                                                
          14    (10)  3-bromo-4-fluoro-phenyl.                                                                   
          15                                                                                                     
          16           Stähle thus discloses ten compounds (although tetrafluorophenyl can                       
          17    be considered a subgenus of compounds because there are four fluoro groups                       
          18    and five positions on which a fluoro can be attached).  The closest Stähle                       
          19    compound is the compound of Formula 7, where the R includes a 5-amino                            
          20    group [―NH2]—the compound identified in Markush member (2), supra.                               
          21    The 6-amino compound identified in Markush member (7), supra, is not as                          

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