Ex Parte Esser et al - Page 22


                Appeal 2006-3252                                                                                 
                Application 09/536,728                                                                           

           1           Esser claims 74-75 and 77-79 also require a substituted amino group                       
           2    at the 3-position.  Accordingly, they fall with independent Esser claim 73.                      
           3           Independent Esser claim 81, directed to a pharmaceutical                                  
           4    composition, has the same relevant limitations as Esser claim 73.                                
           5    Accordingly, it too falls with claim 73.                                                         
           6           The decision of the Examiner rejecting Esser claims 73-75, 77-79 and                      
           7    81 as being unpatentable under 35 U.S.C. § 103(a) over Stähle is reversed.                       
           8                                                                                                     
           9                      Examiner’s § 103 rejection based on Olson                                      
          10           We begin our analysis of the patentability of subject matter of Esser                     
          11    claims 26 and 73-81 by acknowledging that a prior panel held that subject                        
          12    matter to be non-obvious over Olson.  The prior panel's decision reversing                       
          13    the Examiner's rejection based on Olson has not become final.  Likewise, the                     
          14    prior panel entered its decision prior to KSR.  We are obliged to follow KSR.                    
          15    Under the circumstances, we believe that it is appropriate to sua sponte                         
          16    revisit the Examiner's rejection under § 103 of the claims before us based on                    
          17    Olson.  We now affirm that rejection.                                                            
          18                               Prima facie obviousness                                               
          19           The difference between Esser claim 26 (to a specific compound—see                         
          20    Formula 2) and the compound of Example 14 of Olson is that Olson does                            
          21    not explicitly describe a compound with a dimethylamino group                                    
          22    [―N(CH3)2] at the 3-position on the phenyl ring.                                                 
          23           However, Olson describes a fully analogous compound having a                              
          24    diethylamino group [―N(CH2CH3)2] at the 3-position, and like the                                 
          25    compound of Esser claim 26, a methyl on the 2-position of the phenyl ring.                       

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