Ex Parte Bologna et al - Page 9




            Appeal No. 2006-3313                                                                              
            Application No. 10/423,920                                                                        
            claim limitation.”  Pitney Bowes, Inc. v. Hewlett Packard Co., 182 F.3d 1298, 1305, 51            
            USPQ2d 1161, 1165-66 (Fed. Cir. 1999).                                                            


                b.   Anticipation                                                                             
                Claim 16 was not included in the anticipation rejection over Chien but is of similar          
            scope to claim 3, as benzocaine is a cationic treating agent.  Since the application is           
            returned to the examiner for further review and application of additional prior art, we           
            leave it to the examiner to enter a rejection of claim 16 over Chien.  Similarly, the             
            examiner should consider whether claim 18 should be rejected in view of Chien, as                 
            diclofenac is a well known anionic drug and is described at column 6, line 22 of Chien.           


                b)   Obviousness                                                                              
                   With regard to claim 17, we direct the examiner’s attention to U.S. Patent No.             
            6,126,959, describing that terbutaline may be administered via a bioadhesive.  Column             
            2, line 45, column 4, line 49-59, and column 7, lines 13-18.                                      
                   Regarding claim 19, see naproxen disclosed at column 6, line 2 of Moro, U.S.               
            Patent No. 6,585,997.                                                                             
                   We recommend that the examiner consider making a rejection of claims 17 and                
            19 for obviousness over Chien in view of the respective relevant patents discussed                
            herein.   The additional references describe well known active agents known to be                 
            useful for local delivery via a bioadhesive.                                                      

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