Ex Parte Auweter et al - Page 5

                Appeal 2006-3377                                                                               
                Application 09/929,075                                                                         
                pharmaceuticals. The core particles contain the natural carotenoid, and have                   
                a particle size of 0.01 to 5 µm. The microcapsules have mean particle[]                        
                size[s] of 50 to 3,000 µm.  See, particularly, col. 1, lines 6-16, lines 35-42,                
                col. 2, lines 43-58, col. 4, line 45 to col. 5, line 23.”  (OA 3.)                             
                      Akamatsu’s coating material is “based on gelatin” (col. 3, ll. 11-13),                   
                just as Appellants’ coating material can be (Spec. at 6, ll. 1-2); and                         
                Akamatsu’s core material “contains natural carotenoid, [and] an edible oil”                    
                (col. 3, ll. 18-21), just as Appellants’ can (Spec. at 3, l. 45 to 4, l. 2; Spec. at           
                6, ll. 36-38).                                                                                 
                      “Akamatsu et al. specifically state: ‘The natural carotenoid which can                   
                be used herein includes palm oil carotenoid, donariera algae carotenoid,                       
                carrot carotenoid, alfalfa carotenoid, corn carotenoid, and tomato carotenoid                  
                alone or in admixture of two or more. It is preferred that at least two                        
                carotenoids selected from a-carotenoid, b-carotenoid, r-carotenoid, and                        
                lycopene be contained.’ Col. 3, lines 22-32” (Answer 6-7 (emphasis added)).                    
                      Akamatsu teaches their “microcapsule has a strength enough to                            
                protect natural carotenoid from oxidation and deterioration . . . ” (Abstract).                
                      Khachick, Ausick, and Horn are relied upon to address additional                         
                limitations in claims 2-10 and 19 and are not required to determine the                        
                patentability of claim 1.                                                                      
                Other Findings                                                                                 
                      Akamatsu’s suggestion to combine “at least two carotenoids” in their                     
                multicore structures would have motivated the skilled artisan to make the                      
                multicore structure of claim 1 “having at least two cores,” each with a                        
                “different chemical composition.”                                                              



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