Ex Parte Baker et al - Page 9

              Appeal No. 2007-0057                                                                  
              Application No. 10/174,586                                                            

              SEQ ID NO:32 itself.  Therefore, the specification does not adequately                
              describe the claimed genus of polypeptides.                                           
                    Appellants argue that they have provided evidence to show that                  
              PRO270 is similar to thioredoxin and therefore likely to share its activity.          
              (Br. 10.)  This argument is not persuasive, for the reasons discussed above           
              with respect to utility.                                                              
              4.  ANTICIPATION BY LIN, STRAUSBERG, OR TANG                                          
                    Claims 25-32 and 35 stand rejected under 35 U.S.C. § 102(b) as                  
              anticipated by either of Lin5 or Strausberg.6  Similarly, claims 25-32 and 35-        
              37 stand rejected under 35 U.S.C. § 102(a) or § 102(e) as anticipated by              
              Tang.7                                                                                
                    The Examiner argues that Lin and Strausberg both disclose a sequence            
              that “has 100% identity to claimed SEQ ID NO:32,” and therefore                       
              anticipates claims 25-32 and 35.  (Answer 7.)  The Examiner argues that               
                    SEQ ID NO:2374 of Tang et al. has 100 % identity to claimed                     
                    SEQ ID NO:32.  Additionally, Tang et al. teaches a chimera                      
                    polypeptide comprising the instantly claimed polypeptide fused                  
                    to a heterologous polypeptide.  The heterologous polypeptide of                 
                    Tang et al. is an epitope tag and Fc region of an                               
                    immunoglobulin.  Therefore, Tang et al. anticipates the claimed                 
                    invention.                                                                      
              (Id. at 8.)                                                                           
                    Appellants do not dispute that the sequence disclosed by Lin and                
              Strausberg is identical to SEQ ID NO:32.  Nor do Appellants dispute that              
                                                                                                   
              5 Lin, GenBank ID No. Q9Y320 (March 1999).                                            
              6 Strausberg, GenBank ID No. Q9Y320 (Nov. 2000).                                      
              7 Tang et al., WO 01/57188, published August 9, 2001.                                 
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