Ex Parte Arbiser - Page 10

                 Appeal No. 2007-0091                                                                                 
                 Application No. 09/765,491                                                                           

                 carcinoma by administering curcumin.  The Examiner notes that Aggarwal                               
                 teaches that the curcumin composition can be administered in ointment form                           
                 and in a dosage ranging from 1 µg to 100 mg.  (Answer 8.)                                            
                        We agree with the Examiner that Aggarwal would have suggested the                             
                 method of claim 10 to those of ordinary skill in the art.  Aggarwal teaches “a                       
                 method for the treatment of pathological cell proliferative diseases                                 
                 comprising administration to an animal of a pharmacologically effective                              
                 dose of curcumin.”  Page 5, ll. 20-23.  The diseases to be treated include                           
                 psoriasis, basal cell carcinoma and squamous cell carcinoma, all of which                            
                 are recited in claim 10.  Page 5, line 34 to page 6, line 1.                                         
                        Aggarwal teaches that “the curcumin and curcumin analogues are                                
                 administered in a dose of from about 1 microgram to about 100 milligram.”                            
                 Page 6, ll. 9-11.  Finally, Aggarwal teaches that the curcumin-containing                            
                 compositions can be administered topically (page 7, l. 27) in the form of an                         
                 ointment (page 8, l. 10).  We agree with the Examiner that these teachings                           
                 would have suggested the method of instant claim 10 to a person of ordinary                          
                 skill in the art.                                                                                    
                        Appellant argues that “[t]he examiner has cited no evidence why one                           
                 skilled in the art would have any motivation to treat completely different                           
                 disorders with the claimed formulation.”  (Br. 17.)  Aggarwal, however,                              
                 expressly suggests treating at least three of the disorders recited in claim 10.                     
                 Therefore, this argument is unpersuasive.                                                            
                        Appellant also argues that “the examiner has cited no evidence . . .                          
                 why one would have any expectation of success based on a reference using a                           



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