Ex Parte Arbiser - Page 13

                 Appeal No. 2007-0091                                                                                 
                 Application No. 09/765,491                                                                           

                 We affirm the rejection of claim 10 as obvious in view of Arbiser, Thaloor,                          
                 and Aggarwal.  Claims 11, 12, and 19 fall with claim 10.                                             
                                       NEW GROUNDS OF REJECTION                                                       
                        Under the provisions of 37 CFR § 41.50(b), we enter the following                             
                 new grounds of rejection:                                                                            
                        •  Claims 4 and 5 are rejected under 35 U.S.C. § 102(b) as anticipated                        
                 by Andrulis; and                                                                                     
                        •  Claims 4-6 are rejected under 35 U.S.C. § 112, second paragraph, as                        
                 indefinite.                                                                                          
                1.  ANTICIPATION                                                                                      
                        Claims 4 and 5 are rejected under 35 U.S.C. § 102(b) as anticipated                           
                 by Andrulis.  Claim 4 is reproduced above.  Claim 5 depends on claim 4 and                           
                 requires the angiogenesis inhibitor to be applied topically.                                         
                        Andrulis teaches a method of treating “inflammatory and autoimmune                            
                 dermatoses which comprises topical and/or systemic administration of. . .                            
                 thalidomide.”  Abstract.  Thalidomide is one of the angiogenesis inhibitors                          
                 listed in claim 4.  Among other conditions, Andrulis discloses treating                              
                 “molluscum contagiosum.”  Col. 7, ll. 3-4.  This condition reasonably                                
                 appears to be the same as the “molluscum contagious” recited in claim 4.                             
                 Andrulis teaches a method of treating molluscum contagiosum by topical                               
                 administration of thalidomide, and therefore anticipates claims 4 and 5.                             
                 2.  INDEFINITENESS                                                                                   
                        Claims 4-6 are rejected under 35 U.S.C. § 112, second paragraph, as                           
                 indefinite.  Claim 4, and therefore also claims 5 and 6, are directed to a                           
                 “method for inhibiting symptoms associated with angiogenesis in the                                  


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