Ex Parte Wilhelm et al - Page 7


                   Appeal No.  2007-0188                                                                Page 7                     
                   Application No.  10/683,789                                                                                     
                   presumed to be familiar with them.”  In re Rosselet, 347 F.2d 847, 851, 146                                     
                   USPQ 183, 186 (CCPA 1965).                                                                                      
                          Prima facie obviousness based on a combination of references requires                                    
                   that the prior art provide “a reason, suggestion, or motivation to lead an inventor                             
                   to combine those references.”  Pro-Mold and Tool Co. v. Great Lakes Plastics                                    
                   Inc., 75 F.3d 1568, 1573, 37 USPQ2d 1626, 1629 (Fed. Cir. 1996).                                                
                          [E]vidence of a suggestion, teaching, or motivation to combine may                                       
                          flow from the prior art references themselves, the knowledge of one                                      
                          of ordinary skill in the art, or, in some cases, from the nature of the                                  
                          problem to be solved. . . .  The range of sources available, however,                                    
                          does not diminish the requirement for actual evidence.  That is, the                                     
                          showing must be clear and particular.                                                                    
                   In re Dembiczak, 175 F.3d 994, 999, 50 USPQ2d 1614, 1617 (Fed. Cir. 1999)                                       
                   (citations omitted).                                                                                            
                          We agree with the Examiner that Diehl and Springer teach a wearable                                      
                   article within the scope of Appellants’ claimed invention with the exception of                                 
                   detecting a substance that is not a hydrogen ion.  However, we disagree with the                                
                   Examiner’s finding that Ponce and Rittersdorf make up for the deficiencies in                                   
                   Diehl and Springer.                                                                                             
                          Ponce’s study questions the dependability attributed to presumptive tests                                
                   for the presence of blood in a sample under forensic investigation.  Ponce, page                                
                   2.  More particularly, Ponce’s study was concerned about the presence of                                        
                   contaminants in a blood sample that may prevent the achievement of a positive                                   
                   test result.  Id.  Ponce suggests that different reagents are capable of detecting                              
                   different concentrations of blood in a sample and that the level of detection may                               
                   be adversely affected by the presence of contaminants.  Ponce does not suggest                                  





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