Appeal No. 2007-0311
Application No. 10/175,744
prokaryotic cell. (See also, U. S. Patent Nos. 5,700,659 and
5,700,678).
Thus, PDI and molecules related thereto are of interest,
particularly for ability to catalyze the formation of disulfide
bonds. Moreover, these molecules are generally of interest in
the study of redox reactions and related processes. PDI and
related molecules are further described in Darby, et al.,
Biochemistry 34, 11725-11735 (1995). We herein describe the
identification and characterization of novel polypeptides having
homology to protein disulfide isomerase, designated herein as
PRO700 polypeptides.
Page 9.
DISCUSSION
1. CLAIMS
Claims 25-29 are pending and on appeal. The claims have not been
argued separately and therefore stand or fall together. 37 CFR
§ 41.37(c)(1)(vii). Claim 25 is the only independent claim and reads as
follows:
25. An isolated antibody that binds specifically to the polypeptide
of SEQ ID NO: 74.
2. UTILITY
Claims 25-29 stand rejected under 35 U.S.C. §§ 101 and 112, first
paragraph, as lacking patentable utility. The Examiner argues that “[t]he
instant specification and the prior art do not teach how the polypeptide of
SEQ ID NO:74 functions or a specific and well-established utility for the
polypeptide of SEQ ID NO:74 or antibodies that specifically bind said
polypeptide” (Answer 4).
3
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