Ex Parte Cuthbertson et al - Page 4

                Appeal No. 2007-1140                                                                         
                Application No. 10/753,729                                                                   

                      X6 represents a thiol-containing amino acid residue, and                               
                      X7 is absent or represents a biomodifier moiety                                        
                      Z1 represents an antineoplastic agent, a chelating agent or a reporter                 
                      moiety and                                                                             
                      W1 is absent or represents a spacer moiety.                                            






























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