Ex Parte Hage et al - Page 8

                Appeal 2007-1396                                                                             
                Application 10/375,235                                                                       
                catalyst that can bleach stains in a bleaching system that has a low amount of               
                peroxygen bleach, which differs from the claimed compositions in the                         
                absence of a lipoxidase enzyme, the latter disclosed by Baeck. Id. 6-7.  The                 
                Examiner concludes one of ordinary skill in this art would have used                         
                Baeck’s lipoxidase enzyme in Perkins’ compositions with a reasonable                         
                expectation of success because the lipoxidase enzyme is taught to remove                     
                stains, including carotenoid soils, wherein the proportions of the ingredients               
                are as claimed.  Id. 7-8.                                                                    
                      With respect to the first ground of rejection, Appellants contend                      
                Baeck does not disclose, among other things, “ligands/transition metal                       
                catalysts capable of bleaching by air mode,” and “an oxidizable precursor,                   
                especially no disclosure of any linoleates.”  Appellants contend Hermant                     
                does disclose “air mode bleaching of stains” with transition metal catalysts,                
                but does not disclose, among other things, “an oxidizable precursor present,                 
                such as a linoleic acid or salt thereof,” and “an oxidizing enzyme such as                   
                lipoxygenase.” Br. 10-11.  Appellants contend one of ordinary skill in the art               
                would be led away from the combination of lipoxygenases with air mode                        
                bleaching catalysts because there would be no incentive to combine                           
                ingredients that do the same thing.  Id. 11; see also 12.  Appellants further                
                contend the “air mode type transition metal catalysts can synergistically                    
                interact with lipoxygenases to provide an improved result . . . in the presence              
                specifically of linoleic acid or salts thereof.”  Id. 12.  Appellants rely on                
                “[c]omparative experiments . . . reported at [Specification] pages 22-23,”                   
                wherein “[o]f particular effectiveness are Experiments 1 and 1A,” and “good                  
                results were also achieved in Experiments 4 and 4A which are combinations                    
                of lipoxygenase and a transition metal catalyst.”  Id.                                       

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