Ex Parte Seul - Page 16

                  Appeal 2007-1624                                                                                         
                  Application 10/424,662                                                                                   
                  location of the particles on the array and the type of oligonucleotide attached                          
                  to the particles are known.                                                                              
                  48.  The particles and their arrangement in a planar array produced by the                               
                  process of claim 90 are described by Drmanac (FF 20 and 23), including the                               
                  requirement of the claim that the location of the particles on the array and                             
                  the type of oligonucleotide attached to the particles are known3 (FF 24).                                

                                                      ANALYSIS                                                             
                         Anticipation requires a showing that each element of the claim is                                 
                  identifiable in a single reference.  See, e.g., Perricone v. Medicis Pharm.                              
                  Corp., 432 F.3d 1368, 1375, 77 USPQ2d 1321, 1325 (Fed. Cir. 2005).   As                                  
                  described in detail above, Drmanac describes all the elements recited in                                 
                  claims 76-81, 84-86, 88, 89, and 105-108 and therefore anticipates them.                                 
                         Claim 90 is a product-by-process claim.  “[E]ven though product-by-                               
                  process claims are limited by and defined by the process, determination of                               
                  patentability is based on the product itself.” In re Thorpe, 777 F.2d 695, 697,                          
                  227 USPQ 964, 966 (Fed. Cir. 1985).  However, when the process steps                                     
                  confer a structure or characteristic on the product which distinguishes it from                          
                  products made by other processes, the process steps should be considered.                                
                  See, e.g., In re Garnero, 412 F.2d 276, 279, 162 USPQ 221, 223 (CCPA                                     
                  1979).  In this case, the array of oligonucleotides produced by the claimed                              
                  steps of providing and transferring particles to a substrate results in an array                         
                                                                                                                          
                  3 This aspect would also be inferred from Drmanac’s disclosure that the HA                               
                  can be “reused as classic filters” (FF 22; Drmanac, at col. 7, ll. 37-39).  Once                         
                  the HA is used once, and the particles in it are detected, the position of the                           
                  particles and the oligonucleotides attached to the HA would be known.                                    

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