Ex Parte Stryer et al - Page 19

                Appeal 2007-1819                                                                             
                Application 09/886,055                                                                       
                would have lead to a reasonable expectation of success in this case.  See,                   
                e.g., In re O’Farrell, 853 F.2d 894, 903-04, 7 USPQ2d 1673, 1681 (Fed.                       
                Cir. 1988) (“Obviousness does not require absolute predictability of success.                
                . . .  For obviousness under § 103, all that is required is a reasonable                     
                expectation of success.”).  (See also FF 9.)                                                 
                      As previously stated, appropriately framed, the issue is, would it have                
                been obvious to one of ordinary skill in the art to use Burford’s SEQ ID NO:                 
                27 (Appellants’ SEQ ID NO:55) in the assay method taught by Krautwurst,                      
                as required by claim 23?  Based on the record before us, I conclude the                      
                Examiner has made a prima facie case that it would have been obvious to the                  
                skilled artisan—a case that Appellants have not rebutted.                                    
                      Likewise, since Appellants did not separately argue the patentability                  
                of claims 25-33, I would also affirm their rejection pursuant to 37 C.F.R.                   
                § 41.37(c)(1)(vii) (2006).                                                                   


                lbg                                                                                          

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