Ex Parte Fang et al - Page 3

                Appeal  2007-1824                                                                            
                Application 10/639,718                                                                       
                      Barry Schweitzer, “Immunoassays with Rolling Circle DNA                                
                amplification:  A versatile platform for ultrasensitive antigen detection,”                  
                PNAS, 97(18), 10113-10119 (2000).                                                            
                      Lahiri   US 2002/0019015 A1  Feb. 14, 2002                                             
                      Matray  US 6,649,351   Nov. 18, 2003                                                   

                      The rejections as presented by the Examiner are as follows:                            
                1.  Claims 1-15, 18, and 43-51 stand rejected under 35 U.S.C. § 103(a) as                    
                unpatentable over the combination of Lahiri, Matray, and Jordan.                             
                2.  Claims 16, 17, 50, and 51 stand rejected under 35 U.S.C. § 103(a) as                     
                unpatentable over the combination of Lahiri, Matray, Jordan, and                             
                Schweitzer.                                                                                  
                      We affirm.                                                                             

                                               DISCUSSION                                                    
                      Claims 1-15, 18, and 43-51 stand rejected under 35 U.S.C. § 103(a) as                  
                unpatentable over the combination of Lahiri, Matray, and Jordan.  The                        
                claims have not been argued separately and therefore stand or fall together.                 
                37 C.F.R. § 41.37(c)(1)(vii).  Therefore, we limit our discussion to                         
                representative claim 1.  Claim 1 is directed to a method for identifying or                  
                evaluating target compounds capable of modulating ligand-receptor                            
                interactions.  The method comprises four steps:                                              
                      a) providing a plurality of receptor microspots on a substrate to form                 
                an array;                                                                                    
                      b) preparing a cocktail solution of labeled ligands;                                   
                      c) contacting the array with the cocktail solution in the presence of a                
                target compound; and                                                                         

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