Ex Parte Graf et al - Page 8

               Appeal  2007-2018                                                                            
               Application  09/810,377                                                                      

                      FEP layer embedded in virgin FEP) would provide a sheath                              
                      wherein the shaft is distinctly less radiopaque than the distal tip                   
                      section.                                                                              
               (Br. 8.)                                                                                     
                      We are not persuaded by these arguments.  First, the Examiner                         
               combines Parker with Coneys by replacing the polyether block amide in                        
               both the tip and the outer layer of the wall of the main tubular portion with                
               FEP (Answer 8).  This combination does not necessarily require that the FEP                  
               loaded with radiopaque material be surrounded by pure FEP.                                   
                      Second, even if the high loading of FEP with radiopaque material                      
               would make it necessary to surround this highly loaded layer with pure FEP,                  
               claim 1 does not exclude this arrangement.  Instead, claim 1 recites a “distal               
               tip section containing between about 20% and 75% by weight of a                              
               radiopaque material.”  This recitation encompasses a distal tip section                      
               containing highly loaded FEP surrounded by pure FEP, as long as the distal                   
               tip section contains 20-75% by weight radiopaque material.  In addition,                     
               even if this arrangement would dilute the strength of the radiographic signal                
               as compared to a distal tip section containing the same amount of radiopaque                 
               material, but distributed throughout the FEP in the distal tip, which                        
               Appellants have not demonstrated to be the case, this argument would not be                  
               persuasive because claim 1 does not recite the overall strength of the                       
               radiographic signal.                                                                         
                      Furthermore, the Examiner has set forth a prima facie case that the                   
               combination of Parker with Coneys would provide a shaft that is distinctly                   
               less radiopaque than the distal tip.  Parker discloses a catheter having a soft              
               tip including 35-65% by weight tungsten and a main tubular portion                           

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