Ex Parte Sunada et al - Page 9

                Appeal 2007-2049                                                                              
                Application 10/475,223                                                                        
                obviousness.”  Pfizer, Inc. v. Apotex, Inc., 480 F.3d at 1371, 82 USPQ2d at                   
                1338.                                                                                         
                      We also note that Appellants have not explained how the data reflects                   
                a comparison with the closest prior art; nor have they explained how the                      
                comparison of one or two compounds within each of the broad genera of                         
                claimed compounds reflects data that is commensurate in scope with the                        
                claims.  See In re De Blauwe, 736 F.2d 699, 705, 222 USPQ 191, 196 (Fed.                      
                Cir. 1984) (“an applicant relying on comparative tests to rebut a prima facie                 
                case of obviousness must compare his claimed invention to the closest prior                   
                art.”); and In re Greenfield, 571 F.2d 1185, 1189, 197 USPQ 227, 230                          
                (CCPA 1978) (“Establishing that one (or a small number of) species gives                      
                unexpected results is inadequate proof, for ‘it is the view of this court that                
                objective evidence of non-obviousness must be commensurate in scope with                      
                the claims which the evidence is offered to support.’”).                                      

                                            III.  CONCLUSION                                                  
                      Appellants have not overcome the Examiner’s rejection by either                         
                showing insufficient evidence of prima facie obviousness or by rebutting the                  
                prima facie case with sufficient evidence of unexpected results.                              

                                              IV.  DECISION                                                   
                      The decision of the Examiner rejecting claims 4-10, 12, and 14-21                       
                under 35 U.S.C. § 103(a) is affirmed.                                                         





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